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No. 437 here · Grade C

RxPepsDirect review

RxPepsDirect (Peptide RX LLC) is a per-vial compounded GLP-1 telehealth platform offering semaglutide/B12 from $25/vial and tirzepatide/B12 from $45/vial, dispensed through Optimal Balance Pharmacy.

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Semaglutide
From $79/mo (starting dose, visit fee and shipping included, compounded)
Tirzepatide
From $99/mo (starting dose, visit fee and shipping included, compounded)
Coverage
28 states
Brand-name
Compounded only

Prices read from RxPepsDirect's own site on . Providers change pricing without notice — check the current figure before you buy.

On the trackerNewnew to the tracker, no prior reading— New to the tracker on 1 August 2026, and read on the provider's own site rather than taken on trust: we checked https://rxpepsdirect.com/llms.txt on 2026-08-01 and this row reflects what that page says. The line we publish is From $79/mo (starting dose, visit fee and shipping included, compounded). There is no earlier reading of ours to compare it against yet.

The scorecard

RxPepsDirect scored on our six Brief Score factors. See the methodology.

Price Stability48/100
Supply Reliability60/100
Transparency48/100
Access Breadth64/100
Clinical Oversight66/100
Track Record58/100

What we like

  • Industry-lowest GLP-1 pricing: compounded semaglutide from $25/vial, tirzepatide from $45/vial — no subscription or recurring commitment required
  • Real 503A telehealth Rx: licensed NP/PA prescribers + MD medical director (Dr. Jonathan Snipes, NPI 1821250077); patient-specific Rx dispensed by
  • FedEx overnight shipping at $15 flat; ships pre-reconstituted and includes syringes, alcohol wipes, and reusable cooled travel case
  • Independent batch COA testing by Eagle Analytical (FDA-registered, A2LA ISO 17025): 54/54 sterility and endotoxin passes published publicly on
  • No subscription required; $39 flat visit fee covers up to 3 peptides per Rx; pay per vial with no ongoing commitment

The caveats

  • The medication is sold per milligram rather than per month, so the bill rises with every titration — the quoted figures are a starting protocol only, and no price is published for the dose you end up on
  • The $39 medical visit fee is charged on every order, not once, and $15 flat shipping is added to each order as well
  • The dosing behind the quoted price is twice-weekly at 0.15 mg semaglutide, below the 0.25 mg weekly labeled starting dose — a microdose protocol, not the labeled schedule
  • Not available in California, and 28 states in total
  • Compounded semaglutide and tirzepatide are not FDA-approved finished products

The brief

Best for: Readers who want lowest per-vial GLP-1 cost: compounded sema $25, tirz $45, $39 telehealth Rx, no subscription, 28 states. RxPepsDirect (Peptide RX LLC) is a per-vial compounded GLP-1 telehealth platform offering semaglutide/B12 from $25/vial and tirzepatide/B12 from $45/vial, dispensed through Optimal Balance Pharmacy.

Ranked #437 of 546 providers we reviewed — see our #1 pick, CoreAge Rx, for comparison.

Visit RxPepsDirect

Before you decide

The questions readers ask next after reading about RxPepsDirect.

Closest here

The providers scoring nearest RxPepsDirect — the realistic shortlist if you're weighing it.

Weighing RxPepsDirect against one provider in particular? There is a full head-to-head with our top-ranked pick in CoreAge Rx vs RxPepsDirect, and every provider that outranks it is listed on the RxPepsDirect alternatives ranking.

More providers we track (24)

515 more are filed too — see every provider we track, ranked.

Pricing, states and verification reflect RxPepsDirect's public disclosures at last review; the Brief Score is our editorial judgment per the methodology. Prices change — confirm on RxPepsDirect's site. Not medical advice; see our disclosure.

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