Sesame Care review
An established national telehealth marketplace with the widest real brand-name GLP-1 access on the board — Wegovy (pen and pill), Zepbound, Ozempic and Mounjaro — plus provider-by-provider price transparency.
- Semaglutide
- From $149/mo (brand Wegovy pill)
- Tirzepatide
- Brand Zepbound (price varies)
- Coverage
- Nationwide marketplace
- Brand-name
- Yes
The scorecard
Sesame Care scored on our six Brief Score factors. See the methodology.
What we like
- Real FDA-approved brand-name access — Wegovy pen and pill, Zepbound, Ozempic, Mounjaro and Rybelsus
- Established platform (operating since 2018) with LegitScript, BBB accreditation and large third-party review volume
- You choose the provider and see the price up front — genuine marketplace transparency
- Oral routes available (Wegovy pill, Rybelsus)
The caveats
- A generalist marketplace, not a dedicated weight-loss program — lighter ongoing hand-holding than a specialist desk
- Two-part cost (a platform subscription plus the medication) makes the true monthly total harder to compare
- Brand-name cash prices can run high without insurance
The brief
Best for: Shoppers who want genuine FDA-approved brand-name GLP-1s and the ability to pick their own provider and see the price up front, rather than one fixed compounded program. An established national telehealth marketplace with the widest real brand-name GLP-1 access on the board — Wegovy (pen and pill), Zepbound, Ozempic and Mounjaro — plus provider-by-provider price transparency.
Ranked #6 of 34 providers we reviewed — see our #1 pick, CoreAge Rx, for comparison.
Compare with other providers
All 33 other providers we've reviewed, in our overall ranking order.
- #1CoreAge Rx— The steadiest desk on the board: one flat, no-step-up price on both molecules, nationwide, and it hasn't moved.94/100
- #2Eden— A polished, high-disclosure program with strong nationwide coverage — you pay more, but you know exactly what you're paying for.91/100
- #3Trimi— A clean, all-in membership desk that publishes one price on both molecules nationwide and hasn't played the teaser-rate game.89/100
- #4Invigor Medical— An established telehealth pharmacy with a broad metabolic and hormone catalog and a steady price line.88/100
- #5Found— A coaching-first program with the lowest identical price on both molecules — if you want the coaching lock-in that comes with it.88/100
- #7Ro— A heavyweight platform with brand-name access and a polished experience — but it keeps compounded pricing off the record.87/100
- #8ShedRx— A weight-focused program with a low tracked tirzepatide rate and an oral/sublingual route for the needle-averse.87/100
- #9Ondra Health— A rare combination of a rock-bottom $93 semaglutide, brand-name access, LegitScript certification and all-50-state reach.87/100
- #10Vaylen— A full-service, LegitScript-certified desk pairing brand access and an oral route with nationwide reach at a fair mid price.87/100
- #11RxSpan MD— A full-service, LegitScript-certified desk with brand access, an oral route and all-50-state reach — at a premium.87/100
- #12Vytora Health— A rare accredited desk that pairs brand-name access with fair mid-market compounded pricing across all 50 states.87/100
- #13Sprout Health— A LegitScript-certified desk that pairs low-cost compounded semaglutide and tirzepatide with a real brand-name Wegovy and Zepbound path — and a near-frictionless, often visit-free start.86/100
- #14Gala Health— A nationwide desk (Gala GLP-1, from AI Coaching Inc) that opens the door cheap on compounded tirzepatide and — unusually — keeps a brand-name path on the shelf for readers who want it.86/100
- #15Effecty— One of the few accredited desks pairing compounded pricing with brand-name access, nationwide.86/100
- #16NiceRx— An established medication-access brand, now LegitScript-certified and nationwide on both molecules.86/100
- #17Curex— Identical $199 pricing on both molecules, an oral route, LegitScript-certified and nationwide.86/100
- #18Amazon One Medical— The most recognizable name on the board — Amazon's One Medical routes brand-name GLP-1 care through real primary-care clinicians, but keeps pricing off the record.86/100
- #19HealthRX— A LegitScript-certified, physician-supervised desk (healthrx.com) whose real hook is breadth: injectable and a rare oral GLP tablet, on both molecules, with transparent no-insurance monthly pricing.86/100
- #20Telos Rx— The widest published catalog on our board (telosrx.com): compounded semaglutide and tirzepatide in oral and microdosed forms, plus intranasal NAD+, recovery peptides and bioidentical HRT — all compounded, none FDA-approved, on a LegitScript-certified platform.85/100
- #21Enhance MD— A transparent, tiered compounding desk that lays out every price on the ladder up front — semaglutide, tirzepatide, microdose, and a combo line — with NAD+ care sitting alongside.85/100
- #22AgelessRx— A longevity-leaning brand with one of the lowest tracked semaglutide stickers — but a thin disclosure on the rest.85/100
- #23Precision Telemed— A LegitScript-certified, nationwide desk with clean mid-low pricing on both molecules.85/100
- #24BetterMe Rx— A LegitScript-certified, app-adjacent program with an oral option and mid-market pricing nationwide.85/100
- #25Hims & Hers— Mass-market, app-first weight program with nationwide reach — watch the compounded-supply headlines.85/100
- #26TeleCareSpot— A LegitScript-certified, nationwide desk with an oral option — accredited and full-formulary, but priced at the premium end.85/100
- #27RestorLife Med— A LegitScript-certified, nationwide desk that trades a premium sticker for accreditation and clean disclosure.85/100
- #28Henry Meds— A flat-fee compounded pioneer — simple model, but its price has drifted to the higher end of our board.84/100
- #29yourEra— A price-transparent compounded desk that also runs a longevity lane — the sticker is published up front, though the footprint is still thin.84/100
- #30Peak Wellness— A polished, nationwide wellness brand at a premium price — but without a LegitScript badge to back the sticker.83/100
- #31Red Mountain Weight Loss— A long-established, LegitScript-certified weight-loss clinic with a competitive semaglutide line — but a steep $599 tirzepatide and a four-state footprint.83/100
- #32Direct Meds— A newer (2024) compounding desk whose real hook is form: it runs an oral/sublingual line alongside the usual injections, on both molecules, with no membership tacked on.82/100
- #33Mochi Health— A recognizable coaching-forward brand, but availability is capped at roughly 15 states.81/100
- #34Fella Health— A men's-health-focused program with an honest published state list — but a steep $399 tirzepatide line and no accreditation badge.81/100
Pricing, states and verification reflect Sesame Care's public disclosures at last review; the Brief Score is our editorial judgment per the methodology. Prices change — confirm on Sesame Care's site. Not medical advice; see our disclosure.