Enhance MD review

Enhance MD charges $249 a month for semaglutide and $329 for tirzepatide, and it bills every four weeks rather than every calendar month. That distinction is the single most useful number on the page: four-week billing means 13 charges in a year, not 12.

Run that arithmetic before you sign up. Thirteen charges of $249 is $3,237 for a year of semaglutide, where twelve charges would have been $2,988 — an extra $249, a full month of medication, that no headline on the site adds up for you. Tirzepatide has the same shape and a bigger gap: 13 charges of $329 comes to $4,277 against the $3,948 a twelve-month reading suggests. Nothing is hidden here. The plan selector says "Billed every 4 weeks" in plain sight, and medication ships on the same four-week rhythm. It is just very easy to read a four-week price as a monthly one, and that misreading costs about a month a year.

The ladder has four rungs, and the cheaper rungs are prepay blocks rather than discounts applied to a monthly bill. On semaglutide: $249 billed every 4 weeks, $237 a month billed every 12 weeks (a $711 charge), $224 billed every 24 weeks ($1,344), and $212 billed every 48 weeks, which lands as one charge of $2,544. Tirzepatide runs $329 month to month, $313 ($939 every 12 weeks), $296 ($1,776 every 24 weeks) and $280, or $3,360 in a single charge. Read the top rung carefully: it is billed every 48 weeks, not every 52, so the plan people call the twelve-month plan renews about four weeks earlier than a calendar year would.

What the money covers is unusually clean for a compounded provider. The price is flat across every dose — the product pages say "Same Pricing - All Doses" — so titrating up does not raise the bill, which is worth the most on tirzepatide, where climbing to a higher dose is the normal course. Shipping is free. Metabolic lab testing is included at the six-month mark, which is a real clinical inclusion rather than a portal feature. No membership fee and no separate visit charge appeared on the homepage or on either product page when they were read on August 28, 2026.

Ignore the $112. The homepage card reads "Starting at $112 first month" next to "$212 /month", and the $112 is a promotional first order, not an entry rate you keep paying. A dated coupon was running at that check — $100 off plans of three months or longer, $50 off the one-month plan — and dated coupons expire while subscriptions do not. Price this decision off $249 or off $212, then treat any coupon as a one-time rebate on top.

Two things are missing, and one of them may decide it for you. Enhance MD does not publish the states it serves, so whether it can treat you is something you find out partway through an intake rather than before you start one. And everything on offer is compounded: there is no FDA-approved brand-name route, and no oral or sublingual form. Injections only, one every four weeks.

This fits someone who wants to see the whole price ladder before committing and who expects to titrate to a higher dose, since flat per-dose pricing is worth real money on that path. It fits someone willing to prepay: the gap between $249 and $212 is $37 a cycle, which is $444 across the same 48 weeks. It does not fit someone who needs a brand-name option, wants a needle-free route, or wants to confirm state eligibility before handing over health information. And if you take the month-to-month plan because it feels lower-risk, budget for 13 charges, not 12.