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The desk · Semaglutide dispatch · Updated August 2026

The best semaglutide providers, ranked on the facts.

Semaglutide has the longest track record of any GLP-1 here — it was Ozempic, an FDA-approved diabetes drug, years before it became Wegovy. It's also the molecule almost every compounding provider shipped first. We scored the field on what actually matters over a year of treatment, not just the teaser rate.

The ranking

Top 12 semaglutide providers, in Brief-Score order within each group. Providers we have a commercial relationship with are listed first; the score beside each name is ours and does not change because of it. Every score printed on a row is the real one — the reorder moves the row, never the number. CoreAge Rx leads at 94/100; yourEra publishes the cheapest disclosed semaglutide line at From $79/mo — yourEra publishes only a floor; the plan tiers sit behind the intake quiz.

  1. #1

    CoreAge Rx

    Lead pick

    One price on both molecules that does not climb as you titrate — but the headline $99 and $149 are annual-plan rates, paid in full up front.

    Semaglutide:
    $99/mo only on a 12-month plan paid in full ($1,188 in one charge); month-to-month rate not published
    Tirzepatide:
    $149/mo only on a 12-month plan paid in full ($1,788 in one charge); month-to-month rate not published
    States:
    US only; restrictions by state, confirmed at intake
    Trend:
    Stableprice stable
    Visit CoreAge Rx Read the full brief →
  2. #2

    Eden

    A polished, high-disclosure program with strong nationwide coverage — you pay more, but you know exactly what you're paying for.

    Semaglutide:
    $198/mo all-in — $99/mo for the medication plus the $99/mo Eden membership it cannot be bought without ($138 the first month, when membership is $39); compounded
    Tirzepatide:
    $298/mo all-in — $199/mo for the medication plus the required $99/mo membership ($238 the first month); compounded
    States:
    All 50 states
    Trend:
    Fallingprice falling

    FDA warning letter, June 2026 — issued to Eden Health International Inc. dba Eden. See the FDA's warning letter database.

    Visit Eden Read the full brief →
  3. #3

    Trimi

    A clean, all-in membership provider that publishes one price on both molecules nationwide and hasn't played the teaser-rate game.

    Semaglutide:
    $175/mo month-to-month · $99/mo only on a 12-month prepay ($1,188 in one charge)
    Tirzepatide:
    $235/mo month-to-month · $125/mo only on a 12-month prepay ($1,500 in one charge)
    States:
    All 50 states
    Trend:
    Stableprice stable
    Visit Trimi Read the full brief →
  4. #4

    Sesame Care

    An established national telehealth marketplace with the widest real brand-name GLP-1 access in the ranking — Wegovy (pen and pill), Zepbound, Ozempic and Mounjaro — plus provider-by-provider price transparency.

    Semaglutide:
    Brand Wegovy pill from $149/mo at 1.5 and 4 mg only, $299/mo at 9 and 25 mg — plus Sesame care: $59/mo only on the 12-month prepay ($708 in one charge), $69/mo on 6 months, $79/mo on 3 months, otherwise $99 billed every 28 days (13 charges a year)
    Tirzepatide:
    Brand Zepbound vial $299/mo (2.5 mg), $399 (5 mg), $449 (7.5–15 mg); KwikPen $299 / $399 / $499 / $699 (10–15 mg) — plus Sesame care: $59/mo only on the 12-month prepay, $69/mo on 6 months, $79/mo on 3 months, otherwise $99 per 28 days
    States:
    Nationwide marketplace
    Trend:
    Stableprice stable
    Visit Sesame Care Read the full brief →
  5. #5

    ShedRx

    A weight-focused program with a low tracked tirzepatide rate and an oral/sublingual route for the needle-averse.

    Semaglutide:
    $199/mo on the 1-month plan · $179/mo on 6 months · $159/mo only on a 12-month commitment (all plans carry a 2-month minimum)
    Tirzepatide:
    $299/mo on the 1-month plan · $269/mo on 6 months · $239/mo only on a 12-month commitment (all plans carry a 2-month minimum)
    States:
    Not disclosed
    Trend:
    Fallingprice falling
    Visit ShedRx Read the full brief →
  6. #6

    Sprout Health

    A LegitScript-certified provider that pairs low-cost compounded semaglutide and tirzepatide with a real brand-name Wegovy and Zepbound path — and a near-frictionless, often visit-free start.

    Semaglutide:
    $299/mo
    Tirzepatide:
    $349/mo
    States:
    Not disclosed
    Trend:
    Stableprice stable

    FDA warning letter, September 2025 — issued to Sprout Health Partners LLC dba Sprout Health. See the FDA's warning letter database.

    Visit Sprout Health Read the full brief →
  7. #7

    HealthRX

    A LegitScript-certified, physician-supervised provider (healthrx.com) whose real hook is breadth: injectable and a rare oral GLP tablet, on both molecules, with transparent no-insurance monthly pricing.

    Semaglutide:
    $190/mo month-to-month ($149 first month, renews at $165) · $133/mo on a 3-month prepay ($399) · $119/mo on 6 months ($714) · $99/mo only on the 12-month prepay ($1,188 in one charge)
    Tirzepatide:
    $239/mo month-to-month ($193 first month, renews at $214) · $209/mo on a 3-month prepay ($627) · $199/mo on 6 months ($1,194) · $179/mo only on the 12-month prepay ($2,148 in one charge)
    States:
    All 50 states
    Trend:
    Stableprice stable
    Visit HealthRX Read the full brief →
  8. #8

    MadeMed

    Publishes a price for every dose of every route — which makes it easy to brief, and expensive if you stay low.

    Semaglutide:
    $239/mo injectable and $219/mo sublingual on the quarterly plan ($717 / $657 in one charge); $199 and $179 on the 6-month plan. No month-to-month option
    Tirzepatide:
    $399/mo injectable and $299/mo sublingual on the quarterly plan ($1,197 / $897 in one charge); $369 and $279 on the 6-month plan. No month-to-month option
    States:
    40 states for the oral line; injectable semaglutide names 23
    Trend:
    Stableprice stable
    Visit MadeMed Read the full brief →
  9. #9

    Telos Rx

    The widest published catalog in our ranking (telosrx.com): compounded semaglutide and tirzepatide in oral and microdosed forms, plus intranasal NAD+, recovery peptides and bioidentical HRT — all compounded, none FDA-approved, on a LegitScript-certified platform.

    Semaglutide:
    From $99/mo injectable — a floor, not a rate: Telos publishes "as low as $99" and says the price depends on plan length, which is shown only inside the intake
    Tirzepatide:
    From $139/mo injectable · from $116/mo microdosed (microdosing is tirzepatide, not semaglutide) · the needle-free option is one "Oral GLP-1" product covering either molecule, priced from $9 a day on a 3-month prepay
    States:
    Not publicly listed
    Trend:
    Stableprice stable
    Visit Telos Rx Read the full brief →
  10. #10

    Enhance MD

    A transparent, tiered compounding provider that lays out every price on the ladder up front — semaglutide, tirzepatide, microdose, and a combo line — with NAD+ care sitting alongside.

    Semaglutide:
    $249 every 4 weeks month-to-month (13 charges a year); $212/mo only on the 12-month prepay
    Tirzepatide:
    $329 every 4 weeks month-to-month (13 charges a year); $280/mo only on the 12-month prepay
    States:
    Not publicly listed
    Trend:
    Stableprice stable
    Visit Enhance MD Read the full brief →
  11. #11

    yourEra

    Cheapest disclosed

    A price-transparent compounded provider that also runs a longevity lane — the sticker is published up front, though the footprint is still thin.

    Semaglutide:
    From $79/mo — yourEra publishes only a floor; the plan tiers sit behind the intake quiz
    Tirzepatide:
    From $159/mo — yourEra publishes only a floor; the plan tiers sit behind the intake quiz
    States:
    All 50 states
    Trend:
    Stableprice stable
    Visit yourEra Read the full brief →
  12. #12

    Strut Health

    The cheapest oral semaglutide route in the ranking, priced per route rather than per dose — provided you stay on auto-refill.

    Semaglutide:
    $99/mo lozenge · $129/mo injectable (auto-refill price; 30-day supply)
    Tirzepatide:
    $199/mo lozenge · $149/mo injectable (auto-refill price; 30-day supply)
    States:
    49 states (not Arkansas)
    Trend:
    Stableprice stable

    FDA warning letter, February 2026 — issued to Strut Health, LLC dba Strut. See the FDA's warning letter database.

    Visit Strut Health Read the full brief →

Prices are each provider's public disclosures at last check and move fast — confirm before you buy. The Brief Score is our own and is printed unmodified; no provider can buy a point. See the disclosure.

Which ranking is for you

  • Best GLP-1 providers

    The whole field on the six-factor Brief Score — start here if you want the overall pick, not just the cheapest one.

  • Best tirzepatide providers

    The Brief-Score ranking filtered to one molecule — start here if you already know you want tirzepatide (Mounjaro/Zepbound territory).

  • Cheapest GLP-1 right now

    Every tracked provider's semaglutide line, sorted low to high — start here if the sticker price is what matters most.

  • Cheapest semaglutide right now

    Semaglutide only, sorted by price with footprint and brand-vs-compounded flagged — start here if semaglutide is your molecule and price is what matters most.

  • Cheapest tirzepatide right now

    Tirzepatide only, sorted by price with each provider's footprint flagged — start here if tirzepatide is your molecule.

  • Compounded semaglutide

    One molecule, one formulation, ordered by Brief Score — start here if you specifically want compounded (not brand) semaglutide.

  • Compounded tirzepatide

    One molecule, one formulation, ordered by Brief Score — start here if you specifically want compounded (not brand) tirzepatide.

Related reading

Best semaglutide, answered

Who is the best semaglutide provider right now?
On the desk's six-factor Brief Score, CoreAge Rx leads with 94/100 — a flat, no-step-up price on semaglutide, all 50 states, and the steadiest line on our price tracker. yourEra publishes the cheapest disclosed semaglutide at From $79/mo — yourEra publishes only a floor; the plan tiers sit behind the intake quiz.
What is the cheapest semaglutide provider?
yourEra carries the lowest disclosed monthly semaglutide line we track at From $79/mo — yourEra publishes only a floor; the plan tiers sit behind the intake quiz. For the full field sorted strictly on price — with footprint and the compounded-vs-brand split flagged on every row — see the cheapest-semaglutide wire.
Is compounded semaglutide the same as Ozempic or Wegovy?
No. Ozempic was the original FDA-approved brand — cleared for type 2 diabetes years before semaglutide's 2021 weight-loss approval as Wegovy. Most providers here instead dispense compounded semaglutide through licensed pharmacies — a different, usually far cheaper route that is legal but under active FDA attention, and not FDA-approved as a product the way Ozempic and Wegovy are.
Why is semaglutide usually cheaper than tirzepatide?
Semaglutide has been in mass compounding production the longest of the two molecules, and it's the simpler of the two to source and prepare, which tends to show up as a lower headline price across the providers we track. Cheaper is not automatically better — see the Brief Score's price-stability factor rather than the sticker alone.
How does Dose Brief rank semaglutide providers?
Every provider is scored on six measurable factors — price stability, supply reliability, transparency, access breadth, clinical oversight and track record. The Brief Score itself is editorial and is printed unmodified; no provider can buy a higher number. Assume any provider we list may compensate us when a reader signs up — what we write about it reads the same either way, and unflattering findings about a paying provider stay in. See our methodology and disclosure.

Still deciding? See the cheapest semaglutide wire, read why GLP-1 prices move, weigh compounded vs brand-name GLP-1, or compare any two providers head-to-head.

Rankings reflect our published methodology. This page is informational and not medical advice; compounded medications are not FDA-approved brand products. See our medical disclaimer and disclosure.