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The desk · Semaglutide dispatch · Updated August 2026

The best semaglutide providers, ranked on the facts.

Semaglutide has the longest track record of any GLP-1 on this board — it was Ozempic, an FDA-approved diabetes drug, years before it became Wegovy. It's also the molecule almost every compounding desk shipped first. We scored the field on what actually matters over a year of treatment, not just the teaser rate.

The ranked board

Top 12 semaglutide desks, in Brief-Score order within each group. Desks we have a commercial relationship with are listed first; the score beside each name is ours and does not change because of it. Every score printed on a row is the real one — the reorder moves the row, never the number. CoreAge Rx leads at 94/100; Telos Rx publishes the cheapest disclosed semaglutide line at $49/mo (microdosed, annual).

  1. #1

    CoreAge Rx

    Lead pick

    The steadiest desk on the board: one flat, no-step-up price on both molecules, nationwide, and it hasn't moved.

    Semaglutide:
    $149/mo
    Tirzepatide:
    $349/mo
    States:
    All 50 states
    Trend:
    Stableprice stable
    Visit CoreAge Rx Read the full brief →
  2. #2

    Trimi

    A clean, all-in membership desk that publishes one price on both molecules nationwide and hasn't played the teaser-rate game.

    Semaglutide:
    $196/mo
    Tirzepatide:
    $296/mo
    States:
    All 50 states
    Trend:
    Stableprice stable
    Visit Trimi Read the full brief →
  3. #3

    Sesame Care

    An established national telehealth marketplace with the widest real brand-name GLP-1 access on the board — Wegovy (pen and pill), Zepbound, Ozempic and Mounjaro — plus provider-by-provider price transparency.

    Semaglutide:
    From $149/mo (brand Wegovy pill)
    Tirzepatide:
    Brand Zepbound (price varies)
    States:
    Nationwide marketplace
    Trend:
    Stableprice stable
    Visit Sesame Care Read the full brief →
  4. #4

    ShedRx

    A weight-focused program with a low tracked tirzepatide rate and an oral/sublingual route for the needle-averse.

    Semaglutide:
    $199/mo
    Tirzepatide:
    $299/mo
    States:
    Not disclosed
    Trend:
    Fallingprice falling
    Visit ShedRx Read the full brief →
  5. #5

    Sprout Health

    A LegitScript-certified desk that pairs low-cost compounded semaglutide and tirzepatide with a real brand-name Wegovy and Zepbound path — and a near-frictionless, often visit-free start.

    Semaglutide:
    $149/mo
    Tirzepatide:
    $199/mo
    States:
    Not disclosed
    Trend:
    Stableprice stable
    Visit Sprout Health Read the full brief →
  6. #6

    HealthRX

    A LegitScript-certified, physician-supervised desk (healthrx.com) whose real hook is breadth: injectable and a rare oral GLP tablet, on both molecules, with transparent no-insurance monthly pricing.

    Semaglutide:
    $189/mo
    Tirzepatide:
    $349/mo
    States:
    Not publicly listed
    Trend:
    Stableprice stable
    Visit HealthRX Read the full brief →
  7. #7

    MadeMed

    Publishes a price for every dose of every route — which makes it easy to brief, and expensive if you stay low.

    Semaglutide:
    $239/mo injectable · $219/mo sublingual (quarterly)
    Tirzepatide:
    $399/mo injectable · $299/mo sublingual (quarterly)
    States:
    40 states
    Trend:
    Stableprice stable
    Visit MadeMed Read the full brief →
  8. #8

    Telos Rx

    Cheapest disclosed

    The widest published catalog on our board (telosrx.com): compounded semaglutide and tirzepatide in oral and microdosed forms, plus intranasal NAD+, recovery peptides and bioidentical HRT — all compounded, none FDA-approved, on a LegitScript-certified platform.

    Semaglutide:
    $49/mo (microdosed, annual)
    Tirzepatide:
    $99/mo (annual)
    States:
    Not publicly listed
    Trend:
    Stableprice stable
    Visit Telos Rx Read the full brief →
  9. #9

    Enhance MD

    A transparent, tiered compounding desk that lays out every price on the ladder up front — semaglutide, tirzepatide, microdose, and a combo line — with NAD+ care sitting alongside.

    Semaglutide:
    $212/mo
    Tirzepatide:
    $280/mo
    States:
    Not publicly listed
    Trend:
    Stableprice stable
    Visit Enhance MD Read the full brief →
  10. #10

    yourEra

    A price-transparent compounded desk that also runs a longevity lane — the sticker is published up front, though the footprint is still thin.

    Semaglutide:
    $199/mo
    Tirzepatide:
    $299/mo
    States:
    All 50 states
    Trend:
    Stableprice stable
    Visit yourEra Read the full brief →
  11. #11

    Strut Health

    The cheapest oral semaglutide route on the board, priced per route rather than per dose — provided you stay on auto-refill.

    Semaglutide:
    $99/mo lozenge · $149/mo injectable (auto-refill)
    Tirzepatide:
    $199/mo lozenge · $199/mo injectable (auto-refill)
    States:
    49 states (not Alaska)
    Trend:
    Stableprice stable
    Visit Strut Health Read the full brief →
  12. #12

    Gala Health

    A nationwide women's desk (Gala GLP-1, from AI Coaching Inc) whose cheap compounded-tirzepatide door only opens on a yearly subscription — with, unusually, a brand-name path on the shelf beside it.

    Semaglutide:
    Not disclosed
    Tirzepatide:
    $179/mo (yearly subscription)
    States:
    All 50 states
    Trend:
    Stableprice stable
    Visit Gala Health Read the full brief →

Prices are each desk's public disclosures at last check and move fast — confirm before you buy. The Brief Score is our own and is printed unmodified; no desk can buy a point. See the disclosure.

Which board is for you

  • Best GLP-1 providers

    The whole field on the six-factor Brief Score — start here if you want the overall pick, not just the cheapest one.

  • Best tirzepatide providers

    The Brief-Score board filtered to one molecule — start here if you already know you want tirzepatide (Mounjaro/Zepbound territory).

  • Cheapest GLP-1 right now

    Every tracked desk's semaglutide line, sorted low to high — start here if the sticker price is what matters most.

  • Cheapest semaglutide right now

    Semaglutide only, sorted by price with footprint and brand-vs-compounded flagged — start here if semaglutide is your molecule and price is what matters most.

  • Cheapest tirzepatide right now

    Tirzepatide only, sorted by price with each desk's footprint flagged — start here if tirzepatide is your molecule.

  • Compounded semaglutide

    One molecule, one formulation, ordered by Brief Score — start here if you specifically want compounded (not brand) semaglutide.

  • Compounded tirzepatide

    One molecule, one formulation, ordered by Brief Score — start here if you specifically want compounded (not brand) tirzepatide.

Related reading

Best semaglutide, answered

Who is the best semaglutide provider right now?
On the desk's six-factor Brief Score, CoreAge Rx leads with 94/100 — a flat, no-step-up price on semaglutide, all 50 states, and the steadiest line on our price tracker. Telos Rx publishes the cheapest disclosed semaglutide at $49/mo (microdosed, annual).
What is the cheapest semaglutide provider?
Telos Rx carries the lowest disclosed monthly semaglutide line we track at $49/mo (microdosed, annual). For the full field sorted strictly on price — with footprint and the compounded-vs-brand split flagged on every row — see the cheapest-semaglutide wire.
Is compounded semaglutide the same as Ozempic or Wegovy?
No. Ozempic was the original FDA-approved brand — cleared for type 2 diabetes years before semaglutide's 2021 weight-loss approval as Wegovy. Most desks on this board instead dispense compounded semaglutide through licensed pharmacies — a different, usually far cheaper route that is legal but under active FDA attention, and not FDA-approved as a product the way Ozempic and Wegovy are.
Why is semaglutide usually cheaper than tirzepatide?
Semaglutide has been in mass compounding production the longest of the two molecules, and it's the simpler of the two to source and prepare, which tends to show up as a lower headline price across the desks we track. Cheaper is not automatically better — see the Brief Score's price-stability factor rather than the sticker alone.
How does Dose Brief rank semaglutide providers?
Every provider is scored on six measurable factors — price stability, supply reliability, transparency, access breadth, clinical oversight and track record. The Brief Score itself is editorial and is printed unmodified; no desk can buy a higher number. Assume any desk we list may compensate us when a reader signs up — what we write about it reads the same either way, and unflattering findings about a paying desk stay in. See our methodology and disclosure.

Still deciding? See the cheapest semaglutide wire, read why GLP-1 prices move, weigh compounded vs brand-name GLP-1, or compare any two providers head-to-head.

Rankings reflect our published methodology. This page is informational and not medical advice; compounded medications are not FDA-approved brand products. See our medical disclaimer and disclosure.