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Independent GLP-1 newsroomUpdated August 2026

The 5-minute GLP-1 briefing — prices, shortages, and provider moves.

A plain-English desk tracking what GLP-1 telehealth actually costs this week, what's in supply, and which providers earn our six-factor Brief Score. 509 providers here.

The Desk's #1 pick · August 2026

CoreAge Rx tops the ranking — $99/mo semaglutide, $149/mo tirzepatide.

The steadiest desk in the ranking: one flat, no-step-up price on both molecules, nationwide, and it hasn't moved.

Best for: Readers who want a price they can plan around — no teaser-rate reset, no surprise membership fee, both molecules on one account.

CoreAge Rx

94 · A
Semaglutide
$99/mo
Tirzepatide
$149/mo
Coverage
All 50 states
Access
Compounded
Visit CoreAge Rx Read the CoreAge Rx review →

Advertising disclosure · we may earn a commission at no extra cost to you. It never changes a Brief Score. It does decide order: desks we earn on are listed first — see our disclosure.

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This week in GLP-1

The price tracker

Headline monthly compounded prices at our tracked desks, with the direction each moved since our last check. A falling line is good news for you; rising is worth a second look.

ProviderSemaglutideTirzepatideTrend
CoreAge Rx$99/mo$149/moStableprice stable
Trimi$175/mo month-to-month · $99/mo only on a 12-month prepay ($1,188 in one charge)$235/mo month-to-month · $125/mo only on a 12-month prepay ($1,500 in one charge)Stableprice stable
Eden

FDA warning letter, June 2026 — issued to Eden Health International Inc. dba Eden. See the FDA's warning letter database.

$239/mo$349/moStableprice stable
Sesame CareCare $59/mo only on the 12-month prepay, otherwise $99 billed every 28 days (13 charges a year) — plus the drug: brand Wegovy pill from $149/mo at 1.5 and 4 mg only, $299/mo at 9 and 25 mgCare $59/mo on the 12-month prepay, otherwise $99 per 28 days — plus the drug: brand Zepbound vial $299/mo (2.5 mg), $399 (5 mg), $449 (7.5–15 mg); KwikPen $299 / $399 / $499 / $699 (10–15 mg)Stableprice stable
ShedRx$199/mo$299/moFallingprice falling
Sprout Health

FDA warning letter, September 2025 — issued to Sprout Health Partners LLC dba Sprout Health. See the FDA's warning letter database.

$299/mo$349/moStableprice stable
HealthRX$190/mo month-to-month ($99 first month, renews at $165) · $99/mo on a 12-month prepay ($1,188)$239/mo month-to-month ($149 first month, renews at $214) · $179/mo on a 12-month prepay ($2,148)Stableprice stable
MadeMed$239/mo injectable · $219/mo sublingual (quarterly)$399/mo injectable · $299/mo sublingual (quarterly)Stableprice stable
Invigor Medical$199/mo$339/moStableprice stable
Telos Rx$99/mo injectable — the $49 is only the FIRST month of the 12-month prepaid ORAL plan, which renews at $129/mo billed every 48 weeks$139/mo injectable · $129/mo oral · $116/mo microdosed (microdosing is tirzepatide, not semaglutide)Stableprice stable
Enhance MD$249 every 4 weeks month-to-month (13 charges a year); $212/mo only on the 12-month prepay$329 every 4 weeks month-to-month (13 charges a year); $280/mo only on the 12-month prepayStableprice stable
REMEVi$219/mo (all doses, compounded)$319/mo (all doses, compounded)Newnew to the tracker, no prior reading
RoNot disclosedNot disclosedStableprice stable
Ondra Health$93/mo$166/moStableprice stable
Vaylen$179/mo$239/moStableprice stable
Vytora Health$150/mo$200/moStableprice stable
yourEra$199/mo$299/moStableprice stable
Strut Health

FDA warning letter, February 2026 — issued to Strut Health, LLC dba Strut. See the FDA's warning letter database.

$99/mo lozenge · $149/mo injectable (auto-refill)$199/mo lozenge · $199/mo injectable (auto-refill)Stableprice stable
Effecty$160/mo$240/moStableprice stable
NiceRx$199/mo$299/moStableprice stable
Curex

FDA warning letter, September 2025 — issued to Curex. See the FDA's warning letter database.

$199/mo$199/moStableprice stable
Amazon One MedicalNot disclosedNot disclosedStableprice stable
AgelessRx$139/moNot disclosedStableprice stable
Precision Telemed$149/mo$199/moStableprice stable
BetterMe Rx$199/mo$299/moStableprice stable

Prices reflect each desk's public disclosures at last check (August 2026) and change often — confirm on the provider's own site. Not medical advice.

Shortage status

Semaglutide (brand)In supply

Off the FDA shortage list; brand supply resolved.

Tirzepatide (brand)In supply

Off the FDA shortage list since late 2024.

Compounded supplyWatch

Legal but under ongoing FDA scrutiny — sourcing matters.

The ranking

Best GLP-1 providers, by Brief Score

Scored on six factors: price stability · supply reliability · transparency · access breadth · clinical oversight · track record, in Brief-Score order within each group. Desks we have a commercial relationship with are listed first; the score beside each name is ours and does not change because of it.

See the dedicated best GLP-1 providers ranking, the tirzepatide-only cheapest-tirzepatide tracker, the compounded-semaglutide desk list, or read the guides and head-to-head comparisons.

Lead story · #1 here
No. 1Grade A

CoreAge Rx

The steadiest desk in the ranking: one flat, no-step-up price on both molecules, nationwide, and it hasn't moved.

Semaglutide
$99/mo
Tirzepatide
$149/mo
Coverage
All 50 states
Price trend
Stableprice stable
  • Flat monthly price with no intro-rate step-up after month one — the most stable line on our tracker
  • Both compounded semaglutide and tirzepatide on one account
  • Available in all 50 states — the widest reliable footprint in the partner tier
  • Not the rock-bottom price — cheaper teaser tiers exist, but they don't hold
  • No FDA-approved brand-name option (compounded only)
  • Does not yet publicly name its 503A/B pharmacy partner
No. 2Grade B+

Trimi

A clean, all-in membership desk that publishes one price on both molecules nationwide and hasn't played the teaser-rate game.

Semaglutide
$175/mo month-to-month · $99/mo only on a 12-month prepay ($1,188 in one charge)
Tirzepatide
$235/mo month-to-month · $125/mo only on a 12-month prepay ($1,500 in one charge)
Coverage
All 50 states
Price trend
Stableprice stable
  • Both compounded semaglutide and tirzepatide disclosed up front — no quote-to-see-the-price wall
  • Flat membership rate held steady this cycle, with no month-one step-up
  • Available in all 50 states
  • Not the cheapest line in the ranking — several desks undercut its $196 semaglutide
  • Compounded only — no FDA-approved brand-name (Wegovy/Zepbound) route
  • No oral or sublingual option
No. 4Grade B+

Sesame Care

An established national telehealth marketplace with the widest real brand-name GLP-1 access in the ranking — Wegovy (pen and pill), Zepbound, Ozempic and Mounjaro — plus provider-by-provider price transparency.

Semaglutide
Care $59/mo only on the 12-month prepay, otherwise $99 billed every 28 days (13 charges a year) — plus the drug: brand Wegovy pill from $149/mo at 1.5 and 4 mg only, $299/mo at 9 and 25 mg
Tirzepatide
Care $59/mo on the 12-month prepay, otherwise $99 per 28 days — plus the drug: brand Zepbound vial $299/mo (2.5 mg), $399 (5 mg), $449 (7.5–15 mg); KwikPen $299 / $399 / $499 / $699 (10–15 mg)
Coverage
Nationwide marketplace
Price trend
Stableprice stable
  • Real FDA-approved brand-name access — Wegovy pen and pill, Zepbound, Ozempic, Mounjaro and Rybelsus
  • Established platform (operating since 2018) with LegitScript, BBB accreditation and large third-party review volume
  • You choose the provider and see the price up front — genuine marketplace transparency
  • A generalist marketplace, not a dedicated weight-loss program — lighter ongoing hand-holding than a specialist desk
  • Two-part cost (a platform subscription plus the medication) makes the true monthly total harder to compare
  • Brand-name cash prices can run high without insurance
No. 5Grade B+

ShedRx

A weight-focused program with a low tracked tirzepatide rate and an oral/sublingual route for the needle-averse.

Semaglutide
$199/mo
Tirzepatide
$299/mo
Coverage
Not disclosed
Price trend
Fallingprice falling
  • Offers oral/sublingual forms — wider formulary than most
  • Low tracked tirzepatide price
  • Competitive on both molecules
  • States-served not disclosed
  • Compounded only
No. 6Grade B

Sprout Health

A LegitScript-certified desk that pairs low-cost compounded semaglutide and tirzepatide with a real brand-name Wegovy and Zepbound path — and a near-frictionless, often visit-free start.

Semaglutide
$299/mo
Tirzepatide
$349/mo
Coverage
Not disclosed
Price trend
Stableprice stable
  • LegitScript-certified with a listed address and contact line
  • Both compounded (from $299 semaglutide / $349 tirzepatide, with a $150-off first month) and a genuine brand-name Wegovy/Zepbound route
  • Low-friction intake — no labs and often no telehealth visit required
  • Compounded semaglutide and tirzepatide are not FDA-approved
  • No oral or sublingual route — injectable only
  • Thin transparency — no named medical director, and state availability is quiz-gated

FDA warning letter, September 2025 — issued to Sprout Health Partners LLC dba Sprout Health. See the FDA's warning letter database.

No. 7Grade B

HealthRX

A LegitScript-certified, physician-supervised desk (healthrx.com) whose real hook is breadth: injectable and a rare oral GLP tablet, on both molecules, with transparent no-insurance monthly pricing.

Semaglutide
$190/mo month-to-month ($99 first month, renews at $165) · $99/mo on a 12-month prepay ($1,188)
Tirzepatide
$239/mo month-to-month ($149 first month, renews at $214) · $179/mo on a 12-month prepay ($2,148)
Coverage
Not publicly listed
Price trend
Stableprice stable
  • LegitScript-certified (#50087439) — an independent trust signal most compounding desks lack
  • Physician-supervised telehealth with licensed-provider intake
  • Both molecules plus a rare oral GLP tablet — GLP injection ~$189/mo, oral ~$239/mo, GLP+GIP ~$349/mo
  • Core weight-loss product is compounded, which is not FDA-approved
  • Some tiers are company-stated on a thin public site, not checkout-verified
  • Brand tiers are pass-through — brand Ozempic runs ~$1,299/mo
No. 8Grade B

MadeMed

Publishes a price for every dose of every route — which makes it easy to brief, and expensive if you stay low.

Semaglutide
$239/mo injectable · $219/mo sublingual (quarterly)
Tirzepatide
$399/mo injectable · $299/mo sublingual (quarterly)
Coverage
40 states
Price trend
Stableprice stable
  • One published price per route that does not change as the dose climbs, so a titration schedule can be costed exactly
  • Sublingual tablets for BOTH molecules alongside the injections — a needle-free route at a lower price than the injection
  • Six-month plans drop the monthly rate below the quarterly headline
  • Flat-at-every-dose pricing means a reader holding a low dose pays the full-dose rate
  • Billed quarterly rather than monthly, so the real commitment is three months of cost up front
  • Available in 40 states rather than nationwide
No. 10Grade B

Telos Rx

The widest published catalog in our ranking (telosrx.com): compounded semaglutide and tirzepatide in oral and microdosed forms, plus intranasal NAD+, recovery peptides and bioidentical HRT — all compounded, none FDA-approved, on a LegitScript-certified platform.

Semaglutide
$99/mo injectable — the $49 is only the FIRST month of the 12-month prepaid ORAL plan, which renews at $129/mo billed every 48 weeks
Tirzepatide
$139/mo injectable · $129/mo oral · $116/mo microdosed (microdosing is tirzepatide, not semaglutide)
Coverage
Not publicly listed
Price trend
Stableprice stable
  • LegitScript-certified and HIPAA-compliant — a checkable trust signal most compounding desks lack
  • Deepest published menu we track — compounded semaglutide and tirzepatide alongside intranasal NAD+, recovery/GH peptides (sermorelin, ipamorelin, CJC-1295, BPC-157, TB-500) and bioidentical HRT
  • Genuinely needle-free options — oral semaglutide and tirzepatide, plus microdosed tirzepatide — for the injection-averse
  • Every line is compounded and not FDA-approved — including the peptides, several of which are research-grade with thin human evidence
  • ⚠ The headline $49 and $99 are FIRST-MONTH rates that renew at $129 and $139, and the plans bill every 4, 12, 24 or 48 weeks rather than monthly — the "1-month" plan is 13 charges a year, not 12. Pricing outside GLP-1 stays opaque until intake
  • No named clinicians or leadership published, and only a thin base of public reviews

That is the top 8 of 509 desks by Brief Score — the front page, not the whole edition. The full ranking goes deeper with a one-line wire table for the whole field, and every one of the other 501 has its own dispatch on the full index of every desk we track.

See the full ranking

Assume any provider we list may compensate us — see our disclosure. It never changes a Brief Score; it does move a desk up the listing order. Prices, states and verification reflect each provider's public disclosures at last review; the Brief Score is our editorial judgment per the methodology. Prices change — confirm on the provider's site. Not medical advice.