Enhance MD vs ShedRx
Two GLP-1 providers, one scoreboard. We put Enhance MD and ShedRx head-to-head on the published Brief Score — the same six factors, scored the same way.
The verdict
ShedRx takes this head-to-head.
ShedRx scores 87 to 85 on our six-factor Brief Score — Shed offers injection, oral and branded pathways, but its compounded injection prices have a two-month minimum and lower rates require longer terms.
That doesn't make Enhance MD a bad call — it's best for readers who want to see the whole price ladder before they commit and value dose-flat billing plus routine lab work — and who don't need brand-name or oral options. Weigh the six factors below against your own priorities before you decide.
Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Brief Score.
Factor by factor
Both providers scored on the six published Brief Score factors. The higher score in each row is marked. See the methodology.
Price, coverage & the tracker
| Enhance MD | ShedRx | |
|---|---|---|
| Brief Score | 85/100 (B) | 87/100 (B+) |
| Semaglutide | $249 every 4 weeks month-to-month (13 charges a year); $212/mo only on the 12-month prepay | $199/mo on the 1-month plan · $179/mo on 6 months · $159/mo only on a 12-month commitment (all plans carry a 2-month minimum); compounded injection |
| Tirzepatide | $329 every 4 weeks month-to-month (13 charges a year); $280/mo only on the 12-month prepay | $299/mo on the 1-month plan · $269/mo on 6 months · $239/mo only on a 12-month commitment (all plans carry a 2-month minimum); compounded injection |
| Coverage | Not publicly listed | Not disclosed |
| Brand-name access | Compounded only | Yes |
| Oral / sublingual | Injection only | Yes |
| On the tracker | Stableprice stable | Fallingprice falling |
Enhance MD: The ladder is fully published, but its rungs are prepay blocks: $212 and $280 are the 12-MONTH rates, while month-to-month is $249 and $329 — and every plan bills every 4 weeks, so a "monthly" plan is 13 charges a year. The $112 is $212 less a dated SUMMER50 coupon, not an entry rate.
ShedRx: Its lowest tirzepatide rate is $239, and that needs the 12-month commitment; the one-month rung is $299.
● Not sold on either?
CoreAge Rx tops the whole ranking at 94/100.
CoreAge publishes different starting offers across its pages; the advertised annual rates require a full year paid upfront.
Pricing, states and access reflect each provider's public disclosures at last review; the Brief Score is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.