1st Optimal review
1st Optimal is a Michigan-based telehealth and functional-medicine platform offering GLP-1 weight loss medications, including semaglutide and tirzepatide, as once-weekly injections or daily oral tablets.
- Semaglutide
- Not disclosed
- Tirzepatide
- Not disclosed
- Coverage
- Coverage not published
- Brand-name
- Compounded only
Prices read from 1st Optimal's own site on . Providers change pricing without notice — check the current figure before you buy.
The scorecard
1st Optimal scored on our six Brief Score factors. See the methodology.
What we like
- Offers both semaglutide and tirzepatide with injectable and oral formats
- Functional-medicine approach with at-home labs and blood-work interpretation
- Unlimited coaching and ongoing support included
- No long-term contracts
- Board-certified doctors and nurse practitioners referenced
The caveats
- No public monthly pricing disclosed
- No published state availability list
- Compounded vs branded sourcing not clarified on site
- Pricing only revealed after quiz or consultation
The brief
Best for: Patients wanting GLP-1 therapy within a lab-driven functional-medicine program. 1st Optimal is a Michigan-based telehealth and functional-medicine platform offering GLP-1 weight loss medications, including semaglutide and tirzepatide, as once-weekly injections or daily oral tablets.
Ranked #534 of 546 providers we reviewed — see our #1 pick, CoreAge Rx, for comparison.
Before you decide
The questions readers ask next after reading about 1st Optimal.
Closest here
The providers scoring nearest 1st Optimal — the realistic shortlist if you're weighing it.
Weighing 1st Optimal against one provider in particular? There is a full head-to-head with our top-ranked pick in CoreAge Rx vs 1st Optimal, and every provider that outranks it is listed on the 1st Optimal alternatives ranking.
- #531Ways2Well— Ways2Well is a lab-based telehealth and longevity membership founded by Brigham Buhler, offering compounded GLP-1 therapy (semaglutide, with tirzepatide referenced) for weight loss.47/100
- #532Wellspring Longevity Clinic— Wellspring Longevity Clinic is a longevity-focused telehealth service offering compounded GLP-1 (semaglutide) and dual GLP-1/GIP (tirzepatide) for weight management, plus NAD+, peptide therapy.47/100
- #533Zealthy— Zealthy (legal entity FitRX, LLC, recently renamed to Gronk Inc.) offers compounded semaglutide and tirzepatide via an asynchronous telehealth model.47/100
- #535BodyLogicMD— BodyLogicMD is a US telehealth and clinic network (operating since 2003) best known for bioidentical hormone replacement therapy, now offering medically supervised GLP-1 weight management alongside it.46/100
- #536Iron Med RX— Iron Med RX (IRON RX Telehealth) is a Dallas-based online weight-loss provider offering compounded GLP-1 with licensed-provider oversight and home delivery.46/100
- #537PRIMO Health Partners— PRIMO Health Partners is a telehealth practice offering virtual weight-loss consults with clinicians who prescribe GLP-1 medications, including semaglutide and tirzepatide.46/100
More providers we track (24)
- #1 CoreAge Rx94
- #2 Eden91
- #3 Trimi89
- #4 Sesame Care87
- #5 ShedRx87
- #6 Sprout Health86
- #7 HealthRX86
- #8 MadeMed86
- #9 Invigor Medical88
- #10 Telos Rx85
- #11 Enhance MD85
- #12 REMEVi87
- #13 Ro87
- #14 Ondra Health87
- #15 Vaylen87
- #16 Vytora Health87
- #17 No BS RX87
- #18 yourEra84
- #19 Strut Health84
- #20 Effecty86
- #21 NiceRx86
- #22 Curex86
- #23 Amazon One Medical86
- #24 AgelessRx85
515 more are filed too — see every provider we track, ranked.
Pricing, states and verification reflect 1st Optimal's public disclosures at last review; the Brief Score is our editorial judgment per the methodology. Prices change — confirm on 1st Optimal's site. Not medical advice; see our disclosure.