1st Optimal review
1st Optimal is a Michigan-based telehealth and functional-medicine platform offering GLP-1 weight loss medications, including semaglutide and tirzepatide, as once-weekly injections or daily oral tablets.
- Semaglutide
- Not disclosed
- Tirzepatide
- Not disclosed
- Coverage
- Coverage not published
- Brand-name
- Compounded only
The scorecard
1st Optimal scored on our six Brief Score factors. See the methodology.
What we like
- Offers both semaglutide and tirzepatide with injectable and oral formats
- Functional-medicine approach with at-home labs and blood-work interpretation
- Unlimited coaching and ongoing support included
- No long-term contracts
- Board-certified doctors and nurse practitioners referenced
The caveats
- No public monthly pricing disclosed
- No published state availability list
- Compounded vs branded sourcing not clarified on site
- Pricing only revealed after quiz or consultation
The brief
Best for: Patients wanting GLP-1 therapy within a lab-driven functional-medicine program. 1st Optimal is a Michigan-based telehealth and functional-medicine platform offering GLP-1 weight loss medications, including semaglutide and tirzepatide, as once-weekly injections or daily oral tablets.
Ranked #486 of 495 providers we reviewed — see our #1 pick, CoreAge Rx, for comparison.
Closest on the board
The desks scoring nearest 1st Optimal — the realistic shortlist if you're weighing it.
Weighing 1st Optimal against one desk in particular? We file it head to head with our top-ranked pick in CoreAge Rx vs 1st Optimal, and every desk that outranks it is listed on the 1st Optimal alternatives board.
- #483WellMedRx— WellMedRx is a multi-product compounded telehealth platform pairing GLP-1 weight-loss care with TRT, hair-loss, and sexual-health programs under one account.47/100
- #484Wellspring Longevity Clinic— Wellspring Longevity Clinic is a longevity-focused telehealth service offering compounded GLP-1 (semaglutide) and dual GLP-1/GIP (tirzepatide) for weight management, plus NAD+, peptide therapy, and GLP-1…47/100
- #485Zealthy— Zealthy (legal entity FitRX, LLC, recently renamed to Gronk Inc.) offers compounded semaglutide and tirzepatide via an asynchronous telehealth model.47/100
- #487Iron Med RX— Iron Med RX (IRON RX Telehealth) is a Dallas-based online weight-loss provider offering compounded GLP-1 with licensed-provider oversight and home delivery.46/100
- #488PRIMO Health Partners— PRIMO Health Partners is a telehealth practice offering virtual weight-loss consults with clinicians who prescribe GLP-1 medications, including semaglutide and tirzepatide.46/100
- #489Vital Harmony Rx— Vital Harmony Rx is a telehealth platform offering compounded injectable GLP-1 therapy — semaglutide (GLP-1 + B12) and tirzepatide (GLP-1/GIP + B12) — plus a wellness-peptide menu of NAD+, sermorelin, and…46/100
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464 more are filed too — see every desk we track, ranked.
Pricing, states and verification reflect 1st Optimal's public disclosures at last review; the Brief Score is our editorial judgment per the methodology. Prices change — confirm on 1st Optimal's site. Not medical advice; see our disclosure.