CoreAge Rx vs 1st Optimal
Two GLP-1 desks, one scoreboard. We put CoreAge Rx and 1st Optimal head-to-head on the published Brief Score — the same six factors, scored the same way.
CoreAge Rx
The verdict
CoreAge Rx takes this head-to-head.
CoreAge Rx scores 94 to 46 on our six-factor Brief Score — The steadiest desk on the board: one flat, no-step-up price on both molecules, nationwide, and it hasn't moved.
That doesn't make 1st Optimal a bad call — it's best for patients wanting glp-1 therapy within a lab-driven functional-medicine program. Weigh the six factors below against your own priorities before you decide.
Why CoreAge Rx leads: it's our #1 on the board — one flat, no-step-up price on both molecules, nationwide, and the steadiest line on our tracker.
Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Brief Score.
Factor by factor
Both desks scored on the six published Brief Score factors. The higher score in each row is marked. See the methodology.
Price, coverage & the tracker
| CoreAge Rx | 1st Optimal | |
|---|---|---|
| Brief Score | 94/100 (A) | 46/100 (C) |
| Semaglutide | $149/mo | Not disclosed |
| Tirzepatide | $349/mo | Not disclosed |
| Coverage | All 50 states | Coverage not published |
| Brand-name access | Compounded only | Compounded only |
| Oral / sublingual | Injection only | Yes |
| On the tracker | Stableprice stable | Newnew to the tracker, no prior reading |
CoreAge Rx: Flat rate held for a third straight cycle — no first-month teaser to reset.
1st Optimal: New to the tracker on 1 August 2026. This program publishes no monthly medication price, so there is no line for us to track until it does.
Pricing, states and access reflect each provider's public disclosures at last review; the Brief Score is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.