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No. 247 here · Grade C

SkyRx review

SkyRx (sky-rx.co) is a US telehealth weight-loss program offering compounded semaglutide as an injection or oral drops, with compounded tirzepatide listed as coming soon.

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Semaglutide
From $199/mo (all doses, 12-month plan, compounded)
Tirzepatide
Not disclosed
Coverage
Coverage not published
Brand-name
Compounded only

Prices read from SkyRx's own site on . Providers change pricing without notice — check the current figure before you buy.

On the trackerNewnew to the tracker, no prior reading— New to the tracker on 1 August 2026. The published line reads From $199/mo (all doses, 12-month plan, compounded) at our first reading; there is no earlier reading of ours to compare it against yet.

The scorecard

SkyRx scored on our six Brief Score factors. See the methodology.

Price Stability66/100
Supply Reliability69/100
Transparency72/100
Access Breadth46/100
Clinical Oversight76/100
Track Record65/100

What we like

  • All-inclusive 199 dollars per month covers medication, supplies, doctor visit and shipping
  • Offers both injectable and oral semaglutide, dispensed by FDA-registered 503B pharmacies
  • Same-day shipping for orders before 2pm ET in temperature-controlled packaging

The caveats

  • 199 dollars pricing requires a 12-month subscription paid upfront
  • Tirzepatide only listed as coming soon
  • GLP-1s not yet available in all 50 states; specific states not listed

The brief

Best for: Shoppers wanting all-inclusive compounded semaglutide with supplies included. SkyRx (sky-rx.co) is a US telehealth weight-loss program offering compounded semaglutide as an injection or oral drops, with compounded tirzepatide listed as coming soon.

Ranked #247 of 546 providers we reviewed — see our #1 pick, CoreAge Rx, for comparison.

Before you decide

The questions readers ask next after reading about SkyRx.

Closest here

The providers scoring nearest SkyRx — the realistic shortlist if you're weighing it.

Weighing SkyRx against one provider in particular? There is a full head-to-head with our top-ranked pick in CoreAge Rx vs SkyRx, and every provider that outranks it is listed on the SkyRx alternatives ranking.

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515 more are filed too — see every provider we track, ranked.

Pricing, states and verification reflect SkyRx's public disclosures at last review; the Brief Score is our editorial judgment per the methodology. Prices change — confirm on SkyRx's site. Not medical advice; see our disclosure.

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