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No. 291 here · Grade C

Lyfe Rx review

Lyfe Rx offers compounded semaglutide ($289) and compounded tirzepatide ($399).

Visit Lyfe Rx Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the score.

On the record

The FDA issued a warning letter to Lyfe Rx in September 2025. Lyfe Rx keeps its place here and its link is unchanged — but you should know the letter exists before you start care. Read it in the FDA's warning letter database.

Semaglutide
From $225/mo (compounded)
Tirzepatide
From $299/mo (compounded)
Coverage
Coverage not published
Brand-name
Compounded only

Prices read from Lyfe Rx's own site on . Providers change pricing without notice — check the current figure before you buy.

On the trackerNewnew to the tracker, no prior reading— New to the tracker on 1 August 2026. The published line reads From $225/mo (compounded) at our first reading; there is no earlier reading of ours to compare it against yet.

The scorecard

Lyfe Rx scored on our six Brief Score factors. See the methodology.

Price Stability58/100
Supply Reliability71/100
Transparency72/100
Access Breadth50/100
Clinical Oversight79/100
Track Record51/100

What we like

  • Both compounded semaglutide and tirzepatide available
  • Delivery to all 50 states with 1–3 day pharmacy turnaround

The caveats

  • No visible LegitScript or PCAB accreditation
  • Also sells non-prescription supplements ('Tirzepatide Weight Loss Supplement', 'Lipo Burn')
  • Shopify-based e-commerce storefront — less clinical infrastructure
  • FDA issued Lyfe Rx a warning letter in September 2025; the letter is public in FDA's warning-letter database

The brief

Best for: Shoppers modeling the real monthly cost before they commit. Lyfe Rx offers compounded semaglutide ($289) and compounded tirzepatide ($399).

Ranked #291 of 546 providers we reviewed — see our #1 pick, CoreAge Rx, for comparison.

Before you decide

The questions readers ask next after reading about Lyfe Rx.

Closest here

The providers scoring nearest Lyfe Rx — the realistic shortlist if you're weighing it.

Weighing Lyfe Rx against one provider in particular? There is a full head-to-head with our top-ranked pick in CoreAge Rx vs Lyfe Rx, and every provider that outranks it is listed on the Lyfe Rx alternatives ranking.

More providers we track (24)

515 more are filed too — see every provider we track, ranked.

Pricing, states and verification reflect Lyfe Rx's public disclosures at last review; the Brief Score is our editorial judgment per the methodology. Prices change — confirm on Lyfe Rx's site. Not medical advice; see our disclosure.

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