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No. 141 on the board · Grade C

Cost Plus Drugs review

Mark Cuban's transparent-pricing online pharmacy.

Visit Cost Plus Drugs Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the score.
Semaglutide
From $279/mo (brand Ozempic)
Tirzepatide
Not disclosed
Coverage
All 50 states
Brand-name
Yes
On the trackerNewnew to the tracker, no prior readingNew to the tracker on 1 August 2026. The published line reads From $279/mo (brand Ozempic) at our first reading; there is no earlier reading of ours to compare it against yet.

The scorecard

Cost Plus Drugs scored on our six Brief Score factors. See the methodology.

Price Stability58/100
Supply Reliability69/100
Transparency68/100
Access Breadth86/100
Clinical Oversight66/100
Track Record75/100

What we like

  • Transparent pricing: wholesale cost + 15% markup + $5 pharmacy fee, the same for everyone
  • Around $279/mo for branded Ozempic — well below typical retail list prices
  • Mark Cuban's PBM-disrupting pharmacy, praised by Forbes Health, Wired, and KFF Health News
  • Ships to all 50 states; genuine FDA-approved Novo Nordisk Ozempic, not compounded
  • Partnered with 9amHealth so you can get prescribed and fill at Cost Plus pricing

The caveats

  • Fulfillment only — no telehealth intake; you need a prescription from an outside clinician
  • Ozempic is FDA-indicated for type 2 diabetes, not weight management — weight-loss use is off-label
  • Wegovy availability has been spotty — check current stock before assuming it ships
  • No compounded semaglutide or tirzepatide — brand only
  • No clinical follow-up — side-effect monitoring falls to your prescribing clinician

The brief

Best for: Readers who want the cheapest transparent-pricing brand-name Ozempic channel. Mark Cuban's transparent-pricing online pharmacy.

Ranked #141 of 495 providers we reviewed — see our #1 pick, CoreAge Rx, for comparison.

Closest on the board

The desks scoring nearest Cost Plus Drugs — the realistic shortlist if you're weighing it.

Weighing Cost Plus Drugs against one desk in particular? We file it head to head with our top-ranked pick in CoreAge Rx vs Cost Plus Drugs, and every desk that outranks it is listed on the Cost Plus Drugs alternatives board.

More desks we track (24)

464 more are filed too — see every desk we track, ranked.

Pricing, states and verification reflect Cost Plus Drugs's public disclosures at last review; the Brief Score is our editorial judgment per the methodology. Prices change — confirm on Cost Plus Drugs's site. Not medical advice; see our disclosure.

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