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Head-to-head · Brief Score

ShedRx vs RxSpan MD

Two GLP-1 providers, one scoreboard. We put ShedRx and RxSpan MD head-to-head on the published Brief Score — the same six factors, scored the same way.

Higher Brief ScoreNo. 5 · Grade B+

ShedRx

Visit ShedRx Full brief →
vs
No. 101 · Grade C

RxSpan MD

Visit RxSpan MD Full brief →

The verdict

ShedRx takes this head-to-head.

ShedRx scores 87 to 72 on our six-factor Brief Score — Shed offers injection, oral and branded pathways, but its compounded injection prices have a two-month minimum and lower rates require longer terms.

That doesn't make RxSpan MD a bad call — it's best for readers who want to check who is prescribing and who is compounding before they buy, and who will change the pre-selected plan back to monthly unless they actually mean to pay a year up front. Weigh the six factors below against your own priorities before you decide.

Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Brief Score.

Factor by factor

Both providers scored on the six published Brief Score factors. The higher score in each row is marked. See the methodology.

Price Stability
86
66
Supply Reliability
86
82
Transparency
84
56
Access Breadth
85
88
Clinical Oversight
85
78
Track Record
86
62
ShedRxBrief Score 87 · 72RxSpan MD

Price, coverage & the tracker

ShedRxRxSpan MD
Brief Score87/100 (B+)72/100 (C)
Semaglutide$199/mo on the 1-month plan · $179/mo on 6 months · $159/mo only on a 12-month commitment (all plans carry a 2-month minimum); compounded injection$249/mo month-to-month, compounded — the funnel pre-selects a 3-month prepay at $657 up front, and its cheapest rung is $2,327 for a year in one charge
Tirzepatide$299/mo on the 1-month plan · $269/mo on 6 months · $239/mo only on a 12-month commitment (all plans carry a 2-month minimum); compounded injection$329/mo month-to-month, compounded — 3 months bills $927 up front, 12 months $3,228
CoverageNot disclosedAll 50 states claimed — asynchronous review is not available in all of them
Brand-name accessYesYes
Oral / sublingualYesYes
On the trackerFallingprice fallingNewnew to the tracker, no prior reading

ShedRx: Its lowest tirzepatide rate is $239, and that needs the 12-month commitment; the one-month rung is $299.

RxSpan MD: Month-to-month injections cost $249 for semaglutide and $329 for tirzepatide. The $194 and $269 monthly equivalents require upfront payments of $2,327 and $3,228; lower unpublished catalog figures are not purchasable storefront offers.

● Not sold on either?

CoreAge Rx tops the whole ranking at 94/100.

CoreAge publishes different starting offers across its pages; the advertised annual rates require a full year paid upfront.

Keep comparing

Pricing, states and access reflect each provider's public disclosures at last review; the Brief Score is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.