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The shortlist

Alternatives to RxSpan MD

RxSpan MD sits at No. 85 in our ranking with a Brief Score of 72. Here are the GLP-1 desks we'd weigh against it — ranked on the same six-factor Brief Score, top down.

Prefer a straight head-to-head? CoreAge Rx vs RxSpan MD.

Our top alternative

No. 1 here

CoreAge Rx

The steadiest desk in the ranking: one flat, no-step-up price on both molecules, nationwide, and it hasn't moved.

Sema
$99/mo
Tirz
$149/mo
Coverage
All 50 states
Visit CoreAge Rx CoreAge Rx vs RxSpan MD →

More desks worth weighing

No. 38 · Grade C

Luvo Health

79/100

A longevity-leaning telehealth brand ("Longevity-focused care for real life") that publishes a full 4/12/24/52-week term ladder for compounded semaglutide and tirzepatide, plus a real brand-name Ozempic route and a separate NAD+/Sermorelin longevity line — all static pricing, no quiz.

Sema
$249/4-wk injection or $279/4-wk tablets — as low as $45/wk (injection), but only on a prepaid 52-wk term
Coverage
Not disclosed
price stable
Visit vs RxSpan MD →
No. 157 · Grade C

NuDay Rx

69/100

NuDay Rx is a GLP-1 weight-loss telehealth service (on the CareValidate/careGLP platform) that pairs medication with video coaching and lifestyle support.

Sema
From $249/mo (compounded)
Coverage
Coverage not published
new to the tracker, no prior reading
Visit vs RxSpan MD →
No. 195 · Grade C

Synergy Rx

67/100

One of the few desks in this ranking that names both its prescribers and its pharmacies — wrapped around an intro rate that steps up in month two, an $80 visit fee that appears in no headline, and an ODT bundle ladder that costs more per month than not bundling.

Sema
$249/mo ongoing, compounded ($199 first month only) + an $80 visit fee charged whether or not you get medication
Coverage
Coverage not published
new to the tracker, no prior reading
Visit vs RxSpan MD →
No. 125 · Grade C

Layla

71/100

Layla is a US telehealth weight-loss program built around semaglutide, offering compounded semaglutide as injections and as oral dropper drops, plus compounded tirzepatide and a brand-inclusive GLP-1…

Sema
From $237/mo (all doses, compounded)
Coverage
Coverage not published
new to the tracker, no prior reading
Visit vs RxSpan MD →
No. 400 · Grade C

Open Water Rx

56/100

Open Water Rx is a telehealth platform positioned around GLP-1 weight loss and longevity, per its own site.

Sema
From $249/mo (compounded)
Coverage
Coverage not published
new to the tracker, no prior reading
Visit vs RxSpan MD →
No. 162 · Grade C

CLYR Health

68/100

CLYR Health is a Florida-based telehealth pharmacy offering compounded GLP-1 weight-loss injections alongside sexual-health, longevity and wellness treatments.

Sema
From $229/mo (compounded)
Coverage
Coverage not published
new to the tracker, no prior reading
Visit vs RxSpan MD →
No. 33 · Grade B−

Found

81/100

The widest medication bench in the ranking — compounded, brand-name and oral orforglipron — priced off a membership rather than a sticker.

Sema
$289/mo cash month-to-month · $169/mo on a 12-month prepay paid up front ($2,028); the advertised $99 is the in-network INSURANCE rate and still sits before a ~$30 per-visit copay
Coverage
All 50 states
price stable
Visit vs RxSpan MD →
No. 35 · Grade B

Semaglutide Online

83/100

Semaglutide Online is a LegitScript-certified telehealth platform prescribing compounded and brand-name GLP-1/GIP medications nationwide (excluding Alabama).

Sema
From $199/mo (all doses, compounded)
Coverage
All 50 states
new to the tracker, no prior reading
Visit vs RxSpan MD →
Read our full RxSpan MD brief →All comparisons →

Rankings reflect the Dose Brief Score — our editorial judgment per the methodology. Pricing and coverage reflect public disclosures at last review and change often — confirm on each provider's site. Not medical advice; see our disclosure.