Direct Meds sits at No. 30 in our ranking with a Brief Score of 82. Here are the GLP-1 providers we'd weigh against it — ranked on the same six-factor Brief Score, top down.
Prefer a straight head-to-head? CoreAge Rx vs Direct Meds.
One price on both molecules that does not climb as you titrate — but the headline $99 and $149 are annual-plan rates, paid in full up front.
Publishes a price for every dose of every route — which makes it easy to brief, and expensive if you stay low.
An all-in, LegitScript-verified GLP-1 line with a simple sticker price — billed every 4 weeks rather than by the calendar month, and with no named prescriber or pharmacy behind it.
Clume Health charges $259 a month for compounded semaglutide or tirzepatide, the same figure for either, while the two prices on its homepage match nothing it actually sells.
A six-shelf prescription telehealth catalog whose GLP-1 price genuinely holds flat as you titrate — but whose every advertised figure is a twelve-month prepay rate, with the month-to-month price published nowhere.
REMEVi is the first bilingual (English and Spanish) GLP-1 telehealth clinic — care delivered by clinicians trained in both languages, never auto-translated.
Alinwell advertises GLP-1 care from $149 a month, but that is a first-month rate: compounded semaglutide settles at $249 and tirzepatide at $299, charged every 30 days.
Goldspan Health charges $229 for compounded semaglutide and $299 for tirzepatide, billed every 28 days rather than monthly, which comes to 13 charges a year instead of 12.
Fitish offers compounded semaglutide ($219/28 days) and compounded tirzepatide ($339/28 days) including consultation and shipping.
FDA warning letter, June 2026 — issued to FITISH. See the FDA's warning letter database.
On the record
The FDA issued a warning letter to directmeds.com, Inc. dba DirectMeds in September 2025. Direct Meds keeps its place here and its link is unchanged — but you should know the letter exists before you start care. Read it in the FDA's warning letter database.
Rankings reflect the Dose Brief Score — our editorial judgment per the methodology. Pricing and coverage reflect public disclosures at last review and change often — confirm on each provider's site. Not medical advice; see our disclosure.