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Head-to-head · Brief Score

ShedRx vs NiceRx

Two GLP-1 desks, one scoreboard. We put ShedRx and NiceRx head-to-head on the published Brief Score — the same six factors, scored the same way.

Higher Brief ScoreNo. 5 · Grade B+

ShedRx

Visit ShedRx Full brief →
vs
No. 20 · Grade B

NiceRx

Visit NiceRx Full brief →

The verdict

ShedRx takes this head-to-head.

ShedRx scores 87 to 86 on our six-factor Brief Score — A weight-focused program with a low tracked tirzepatide rate and an oral/sublingual route for the needle-averse.

That doesn't make NiceRx a bad call — it's best for readers who want a longer-tenured, accredited name over an unknown newcomer. Weigh the six factors below against your own priorities before you decide.

Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Brief Score.

Factor by factor

Both desks scored on the six published Brief Score factors. The higher score in each row is marked. See the methodology.

Price Stability
86
85
Supply Reliability
86
86
Transparency
84
87
Access Breadth
85
87
Clinical Oversight
85
86
Track Record
86
84
ShedRxBrief Score 87 · 86NiceRx

Price, coverage & the tracker

ShedRxNiceRx
Brief Score87/100 (B+)86/100 (B)
Semaglutide$199/mo on the 1-month plan · $179/mo on 6 months · $159/mo only on a 12-month commitment (all plans carry a 2-month minimum)$199/mo
Tirzepatide$299/mo on the 1-month plan · $269/mo on 6 months · $239/mo only on a 12-month commitment (all plans carry a 2-month minimum)$299/mo
CoverageNot disclosedAll 50 states
Brand-name accessCompounded onlyCompounded only
Oral / sublingualYesInjection only
On the trackerFallingprice fallingStableprice stable

ShedRx: Its $239 tirzepatide is the lowest rate among our partners, but only on the 12-month commitment — the 1-month rung is $299.

NiceRx: $199 sema / $299 tirz nationwide; LegitScript-certified, established operator.

Not sold on either?

CoreAge Rx tops the whole ranking at 94/100.

One price on both molecules that does not climb as you titrate — but the headline $99 and $149 are annual-plan rates, paid in full up front.

Keep comparing

Pricing, states and access reflect each provider's public disclosures at last review; the Brief Score is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.