NuDay Rx vs Synergy Rx
Two GLP-1 desks, one scoreboard. We put NuDay Rx and Synergy Rx head-to-head on the published Brief Score — the same six factors, scored the same way.
NuDay Rx
The verdict
NuDay Rx takes this head-to-head.
NuDay Rx scores 69 to 67 on our six-factor Brief Score — NuDay Rx is a GLP-1 weight-loss telehealth service (on the CareValidate/careGLP platform) that pairs medication with video coaching and lifestyle support.
That doesn't make Synergy Rx a bad call — it's best for readers who want to verify who is actually prescribing and compounding their medication, and who will read past the first-month rate to the $249 or $399 they will pay from month two. Weigh the six factors below against your own priorities before you decide.
Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Brief Score.
Factor by factor
Both desks scored on the six published Brief Score factors. The higher score in each row is marked. See the methodology.
Price, coverage & the tracker
| NuDay Rx | Synergy Rx | |
|---|---|---|
| Brief Score | 69/100 (C) | 67/100 (C) |
| Semaglutide | From $249/mo (compounded) | $249/mo ongoing, compounded ($199 first month only) + an $80 visit fee charged whether or not you get medication |
| Tirzepatide | From $329/mo (compounded) | $399/mo ongoing, compounded ($349 first month only); the ODT bundles price HIGHER, at $399.67–$399.92/mo |
| Coverage | Coverage not published | Coverage not published |
| Brand-name access | Yes | Yes |
| Oral / sublingual | Yes | Yes |
| On the tracker | Newnew to the tracker, no prior reading | Newnew to the tracker, no prior reading |
NuDay Rx: New to the tracker on 1 August 2026. The published line reads From $249/mo (compounded) at our first reading; there is no earlier reading of ours to compare it against yet.
Synergy Rx: First reading, 7 August 2026. Ongoing month-to-month is $249 semaglutide and $399 tirzepatide; the $199 and $349 figures carried in older datasets are first-month-only rates. An $80 telehealth visit fee sits outside every headline and is charged whether or not medication is dispensed.
● Not sold on either?
CoreAge Rx tops the whole ranking at 94/100.
The steadiest desk in the ranking: one flat, no-step-up price on both molecules, nationwide, and it hasn't moved.
Pricing, states and access reflect each provider's public disclosures at last review; the Brief Score is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.