MyStart Health vs SkinnyRx
Two GLP-1 desks, one scoreboard. We put MyStart Health and SkinnyRx head-to-head on the published Brief Score — the same six factors, scored the same way.
MyStart Health
FDA warning letter, September 2025 — issued to Matthew Stern, CEO MyStart Health LLC.. See the FDA's warning letter database.
SkinnyRx
FDA warning letter, February 2026 — issued to Lean Rx, Inc. dba SkinnyRx. See the FDA's warning letter database.
The verdict
MyStart Health takes this head-to-head.
MyStart Health scores 71 to 58 on our six-factor Brief Score — MyStart Health offers all-inclusive compounded semaglutide and tirzepatide at $299/month with a price-lock guarantee, same-day physician consultations, and 24/7 care team access.
That doesn't make SkinnyRx a bad call — it's best for readers who will not inject and want a tablet at no premium over the injection, and who will check which term a "$199" is attached to before treating it as a monthly bill. Weigh the six factors below against your own priorities before you decide.
Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Brief Score.
Factor by factor
Both desks scored on the six published Brief Score factors. The higher score in each row is marked. See the methodology.
Price, coverage & the tracker
| MyStart Health | SkinnyRx | |
|---|---|---|
| Brief Score | 71/100 (C) | 58/100 (C) |
| Semaglutide | From $299/mo (all doses, compounded) | $349/mo month-to-month, compounded — the advertised $199 is the 12-month rung, billed as $2,388 in one payment |
| Tirzepatide | From $299/mo (all doses, compounded) | $399/mo month-to-month, compounded, injection or tablet at the same price — the advertised $299 is the 12-month rung, billed as $3,588 in one payment |
| Coverage | Coverage not published | 47 states + Washington DC — not Alabama, Louisiana or Mississippi |
| Brand-name access | Compounded only | Compounded only |
| Oral / sublingual | Yes | Yes |
| On the tracker | Newnew to the tracker, no prior reading | Newnew to the tracker, no prior reading |
MyStart Health: New to the tracker on 1 August 2026. The published line reads From $299/mo (all doses, compounded) at our first reading; there is no earlier reading of ours to compare it against yet.
SkinnyRx: First reading, 8 August 2026. Month-to-month is $349 semaglutide and $399 tirzepatide, and the tirzepatide tablet costs exactly what the tirzepatide injection costs at all four terms. The "as low as $199 / $299" the site advertises are the twelve-month rungs, charged as $2,388 and $3,588 up front and auto-renewing annually. The separate microdose line costs the same as full dose at every shared term and floors higher, at $229 and $319, because it stops at eight months.
● Not sold on either?
CoreAge Rx tops the whole ranking at 94/100.
The steadiest desk in the ranking: one flat, no-step-up price on both molecules, nationwide, and it hasn't moved.
Pricing, states and access reflect each provider's public disclosures at last review; the Brief Score is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.