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Head-to-head · Brief Score

MadeMed vs PCOS Sisters

Two GLP-1 desks, one scoreboard. We put MadeMed and PCOS Sisters head-to-head on the published Brief Score — the same six factors, scored the same way.

Higher Brief ScoreNo. 8 · Grade B

MadeMed

Visit MadeMed Full brief →
vs
No. 168 · Grade C

PCOS Sisters

Visit PCOS Sisters Full brief →

The verdict

MadeMed takes this head-to-head.

MadeMed scores 86 to 68 on our six-factor Brief Score — Publishes a price for every dose of every route — which makes it easy to brief, and expensive if you stay low.

That doesn't make PCOS Sisters a bad call — it's best for readers who want women with pcos seeking glp-1 weight and metabolic care. Weigh the six factors below against your own priorities before you decide.

Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Brief Score.

Factor by factor

Both desks scored on the six published Brief Score factors. The higher score in each row is marked. See the methodology.

Price Stability
92
44
Supply Reliability
84
73
Transparency
94
80
Access Breadth
76
76
Clinical Oversight
84
70
Track Record
82
74
MadeMedBrief Score 86 · 68PCOS Sisters

Price, coverage & the tracker

MadeMedPCOS Sisters
Brief Score86/100 (B)68/100 (C)
Semaglutide$239/mo injectable · $219/mo sublingual (quarterly)From $150/mo (plus a separate fee, compounded)
Tirzepatide$399/mo injectable · $299/mo sublingual (quarterly)From $150/mo (plus a separate fee, compounded)
Coverage40 states12 states
Brand-name accessCompounded onlyYes
Oral / sublingualYesYes
On the trackerStableprice stableNewnew to the tracker, no prior reading

MadeMed: Publishes one price per route that holds at every dose — the cleanest dose-to-price mapping we track.

PCOS Sisters: New to the tracker on 1 August 2026. The published line reads From $150/mo (plus a separate fee, compounded) at our first reading; there is no earlier reading of ours to compare it against yet.

Not sold on either?

CoreAge Rx tops the whole board at 94/100.

The steadiest desk on the board: one flat, no-step-up price on both molecules, nationwide, and it hasn't moved.

Keep comparing

Pricing, states and access reflect each provider's public disclosures at last review; the Brief Score is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.