RxSpan MD vs Vaylen
Two GLP-1 desks, one scoreboard. We put RxSpan MD and Vaylen head-to-head on the published Brief Score — the same six factors, scored the same way, no pay-to-win placement.
The verdict
Too close to call on the Brief Score.
RxSpan MD and Vaylen are level at 87/100. The scores won't separate them, so the pick comes down to fit: RxSpan MD for readers who want the widest formulary — brand, compounded and oral — from one accredited nationwide desk. Vaylen for readers who want brand, compounded and oral options from one accredited nationwide desk without a premium sticker.
Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Brief Score.
Factor by factor
Both desks scored on the six published Brief Score factors. The higher score in each row is marked. See the methodology.
Price, coverage & the tracker
| RxSpan MD | Vaylen | |
|---|---|---|
| Brief Score | 87/100 (B+) | 87/100 (B+) |
| Semaglutide | $249/mo | $179/mo |
| Tirzepatide | $329/mo | $239/mo |
| Coverage | All 50 states | All 50 states |
| Brand-name access | Yes | Yes |
| Oral / sublingual | Yes | Yes |
| On the tracker | Stableprice stable | Stableprice stable |
RxSpan MD: $249 sema / $329 tirz premium line; brand + oral + LegitScript, all 50 states.
Vaylen: $179 sema / $239 tirz; brand + oral + LegitScript across all 50 states.
● Not sold on either?
CoreAge Rx tops the whole board at 94/100.
The steadiest desk on the board: one flat, no-step-up price on both molecules, nationwide, and it hasn't moved.
Pricing, states and access reflect each provider's public disclosures at last review; the Brief Score is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.